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Self-cleavage of the glmS ribozyme core is controlled by a fragile folding element

Riboswitches modulate gene expression in response to small-molecule ligands. Switching is generally thought to occur via the stabilization of a specific RNA structure conferred by binding the cognate ligand. However, it is unclear whether any such stabilization occurs for riboswitches whose ligands...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Savinov, Andrew, Block, Steven M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255189/
https://ncbi.nlm.nih.gov/pubmed/30397151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812122115
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