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Analysis of Metal Ion-Dependence in glmS Ribozyme Self-Cleavage and Coenzyme Binding

The bacterial glmS ribozyme is a mechanistically unique functional RNA among both riboswitches and RNA catalysts. Its self-cleavage activity is the basis of riboswitch regulation of glucosamine-6-phosphate (GlcN6P) production, and catalysis requires GlcN6P as a coenzyme. Previous work has shown that...

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Autors principals: Klawuhn, Kevin, Jansen, Joshua A., Souchek, Joshua, Soukup, Garrett A., Soukup, Juliane K.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251013/
https://ncbi.nlm.nih.gov/pubmed/21108273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201000544
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