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Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification

Human papillomaviruses (HPVs) cause epithelial proliferative diseases. Persistent infection of the mucosal epithelia by the high-risk genotypes can progress to high-grade dysplasia and cancers. Viral transcription and protein activities are intimately linked to regulation by histone acetyltransferas...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Banerjee, N. Sanjib, Moore, Dianne W., Broker, Thomas R., Chow, Louise T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255162/
https://ncbi.nlm.nih.gov/pubmed/30385631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801156115
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