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The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo

Interactions between histone deacetylase inhibitors (HDACIs) and the novel proteasome inhibitor carfilzomib (CFZ) were investigated in GC- and activated B-cell–like diffuse large B-cell lymphoma (ABC-DLBCL) cells. Coadministration of subtoxic or minimally toxic concentrations of CFZ) with marginally...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dasmahapatra, Girija, Lembersky, Dmitry, Kramer, Lora, Fisher, Richard I., Friedberg, Jonathan, Dent, Paul, Grant, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881506/
https://ncbi.nlm.nih.gov/pubmed/20233973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-257261
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