The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo

Interactions between histone deacetylase inhibitors (HDACIs) and the novel proteasome inhibitor carfilzomib (CFZ) were investigated in GC- and activated B-cell–like diffuse large B-cell lymphoma (ABC-DLBCL) cells. Coadministration of subtoxic or minimally toxic concentrations of CFZ) with marginally...

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Detalhes bibliográficos
Main Authors: Dasmahapatra, Girija, Lembersky, Dmitry, Kramer, Lora, Fisher, Richard I., Friedberg, Jonathan, Dent, Paul, Grant, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881506/
https://ncbi.nlm.nih.gov/pubmed/20233973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-257261
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