Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC- DLBCL cells in vitro and in vivo

Interactions between the the irreversible proteasome inhibitor carfilzomib (CFZ) and the pan-BH3 mimetic obatoclax (Obato) were examined in GC- and ABC-DLBCL cells. Co-treatment with minimally toxic concentrations of CFZ (i.e., 2–6 nM) and sub-toxic concentrations of obato (0.05–2.0μM) synergistical...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dasmahapatra, Girija, Lembersky, Dmitry, Son, Minkyeong P., Patel, Hiral, Peterson, Derick, Attkisson, Elisa, Fisher, Richard I., Friedberg, Jonathan W., Dent, Paul, Grant, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601737/
https://ncbi.nlm.nih.gov/pubmed/22411899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0021
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados