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Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

BACKGROUND: Ebola virus (EBOV) mainly targets myeloid cells; however, extensive death of T cells is often observed in lethal infections. We have previously shown that EBOV VP40 in exosomes causes recipient immune cell death. METHODS: Using VP40-producing clones, we analyzed donor cell cycle, extrace...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: Pleet, Michelle L, Erickson, James, DeMarino, Catherine, Barclay, Robert A, Cowen, Maria, Lepene, Benjamin, Liang, Janie, Kuhn, Jens H, Prugar, Laura, Stonier, Spencer W, Dye, John M, Zhou, Weidong, Liotta, Lance A, Aman, M Javad, Kashanchi, Fatah
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249571/
https://ncbi.nlm.nih.gov/pubmed/30169850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy472
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