Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

BACKGROUND: Ebola virus (EBOV) mainly targets myeloid cells; however, extensive death of T cells is often observed in lethal infections. We have previously shown that EBOV VP40 in exosomes causes recipient immune cell death. METHODS: Using VP40-producing clones, we analyzed donor cell cycle, extrace...

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Pubblicato in:J Infect Dis
Autori principali: Pleet, Michelle L, Erickson, James, DeMarino, Catherine, Barclay, Robert A, Cowen, Maria, Lepene, Benjamin, Liang, Janie, Kuhn, Jens H, Prugar, Laura, Stonier, Spencer W, Dye, John M, Zhou, Weidong, Liotta, Lance A, Aman, M Javad, Kashanchi, Fatah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Supplement Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249571/
https://ncbi.nlm.nih.gov/pubmed/30169850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy472
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