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Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

BACKGROUND: Ebola virus (EBOV) mainly targets myeloid cells; however, extensive death of T cells is often observed in lethal infections. We have previously shown that EBOV VP40 in exosomes causes recipient immune cell death. METHODS: Using VP40-producing clones, we analyzed donor cell cycle, extrace...

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Detalles Bibliográficos
Publicado en:J Infect Dis
Main Authors: Pleet, Michelle L, Erickson, James, DeMarino, Catherine, Barclay, Robert A, Cowen, Maria, Lepene, Benjamin, Liang, Janie, Kuhn, Jens H, Prugar, Laura, Stonier, Spencer W, Dye, John M, Zhou, Weidong, Liotta, Lance A, Aman, M Javad, Kashanchi, Fatah
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249571/
https://ncbi.nlm.nih.gov/pubmed/30169850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy472
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