Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

BACKGROUND: Ebola virus (EBOV) mainly targets myeloid cells; however, extensive death of T cells is often observed in lethal infections. We have previously shown that EBOV VP40 in exosomes causes recipient immune cell death. METHODS: Using VP40-producing clones, we analyzed donor cell cycle, extrace...

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Vydáno v:J Infect Dis
Hlavní autoři: Pleet, Michelle L, Erickson, James, DeMarino, Catherine, Barclay, Robert A, Cowen, Maria, Lepene, Benjamin, Liang, Janie, Kuhn, Jens H, Prugar, Laura, Stonier, Spencer W, Dye, John M, Zhou, Weidong, Liotta, Lance A, Aman, M Javad, Kashanchi, Fatah
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Supplement Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249571/
https://ncbi.nlm.nih.gov/pubmed/30169850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy472
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