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HIV-1 Envelope Glycoproteins Induce the Production of TNF-α and IL-10 in Human Monocytes by Activating Calcium Pathway

Human HIV-1 infection leads inevitably to a chronic hyper-immune-activation. However, the nature of the targeted receptors and the pathways involved remain to be fully elucidated. We demonstrate that X4-tropic gp120 induced the production of TNF-α and IL-10 by monocytes through activation of a cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Planès, Rémi, Serrero, Manutea, Leghmari, Kaoutar, BenMohamed, Lbachir, Bahraoui, Elmostafa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249280/
https://ncbi.nlm.nih.gov/pubmed/30464243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35478-1
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