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Maternal immune activation in rats blunts brain cytokine and kynurenine pathway responses to a second immune challenge in early adulthood.
Maternal immune activation (MIA) with the viral mimic poly I:C provides an established rodent model for studying schizophrenia (SZ) and other human neurodevelopmental disorders. Postnatal infections are additional risk factors in SZ and may cumulatively contribute to the emergence of pathophysiology...
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| Publicado no: | Prog Neuropsychopharmacol Biol Psychiatry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249106/ https://ncbi.nlm.nih.gov/pubmed/30267854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2018.09.011 |
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