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Assessment of Prenatal Kynurenine Metabolism using Tissue Slices: Focus on the Neosynthesis of Kynurenic Acid in Mice

Several lines of evidence support the hypothesis that abnormally elevated brain levels of kynurenic acid (KYNA), a metabolite of the kynurenine pathway (KP) of tryptophan degradation, play a pathophysiologically significant role in schizophrenia and other major neurodevelopmental disorders. Studies...

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Detalhes bibliográficos
Publicado no:Dev Neurosci
Main Authors: Notarangelo, Francesca M, Beggiato, Sarah, Schwarcz, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732239/
https://ncbi.nlm.nih.gov/pubmed/31117076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000499736
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