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Interim monitoring for non-inferiority trials: minimizing patient exposure to inferior therapies

The goal of a non-inferiority randomized trial is to demonstrate that an experimental treatment is not unacceptably worse than a standard treatment. The experimental treatment is known to have less toxicity or other quality-of-life benefits when compared with the standard treatment, so that a small...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Ann Oncol
Asıl Yazarlar: Korn, E L, Freidlin, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248434/
https://ncbi.nlm.nih.gov/pubmed/29267937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx788
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