Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

We apply integrative approaches to expression quantitative loci (eQTLs) from 44 tissues from the GTEx Project and genome-wide association study (GWAS) data. About 60% of known trait-associated loci are in linkage disequilibrium with a cis-eQTL, over half of which were not found in previous large-sca...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Gamazon, Eric R., Segrè, Ayellet V., van de Bunt, Martijn, Wen, Xiaoquan, Xi, Hualin S., Hormozdiari, Farhad, Ongen, Halit, Konkashbaev, Anuar, Derks, Eske M., Aguet, François, Quan, Jie, Nicolae, Dan L., Eskin, Eleazar, Kellis, Manolis, Getz, Gad, McCarthy, Mark I., Dermitzakis, Emmanouil T., Cox, Nancy J., Ardlie, Kristin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248311/
https://ncbi.nlm.nih.gov/pubmed/29955180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0154-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados