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Thalidomide-type teratogenicity: structure–activity relationships for congeners

Unravelling the molecular basis of thalidomide embryotoxicity, which is remarkably species–specific, is challenging in view of its low toxicity in the mature animal. Employing data derived solely from proven sensitive primate species or susceptible strains of rabbit, the structure–activity relations...

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Vydáno v:Toxicol Res (Camb)
Hlavní autoři: Smith, R. L., Mitchell, S. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248049/
https://ncbi.nlm.nih.gov/pubmed/30542600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00187a
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