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Thalidomide-type teratogenicity: structure–activity relationships for congeners

Unravelling the molecular basis of thalidomide embryotoxicity, which is remarkably species–specific, is challenging in view of its low toxicity in the mature animal. Employing data derived solely from proven sensitive primate species or susceptible strains of rabbit, the structure–activity relations...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Smith, R. L., Mitchell, S. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248049/
https://ncbi.nlm.nih.gov/pubmed/30542600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00187a
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