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Thalidomide-type teratogenicity: structure–activity relationships for congeners

Unravelling the molecular basis of thalidomide embryotoxicity, which is remarkably species–specific, is challenging in view of its low toxicity in the mature animal. Employing data derived solely from proven sensitive primate species or susceptible strains of rabbit, the structure–activity relations...

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Dettagli Bibliografici
Pubblicato in:Toxicol Res (Camb)
Autori principali: Smith, R. L., Mitchell, S. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248049/
https://ncbi.nlm.nih.gov/pubmed/30542600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8tx00187a
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