Antifibrotic Effects of Hepatocyte Growth Factor on Endothelial-to-Mesenchymal Transition via Transforming Growth Factor-Beta1 (TGF-β1)/Smad and Akt/mTOR/P70S6K Signaling Pathways

BACKGROUND: The related mechanisms involved in allograft interstitial fibrosis and chronic allograft dysfunction (CAD), following renal transplant, remain largely unknown. Here, we explored the role of hepatocyte growth factor (HGF) treatment on the endothelial-to-mesenchymal transition (EndMT) as a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Transplant
Päätekijät: Wang, Zijie, Fei, Shuang, Suo, Chuanjian, Han, Zhijian, Tao, Jun, Xu, Zhen, Zhao, Chunchun, Tan, Ruoyun, Gu, Min
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Scientific Literature, Inc. 2018
Aiheet:
Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248046/
https://ncbi.nlm.nih.gov/pubmed/29292365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.906700
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