Antifibrotic Effects of Hepatocyte Growth Factor on Endothelial-to-Mesenchymal Transition via Transforming Growth Factor-Beta1 (TGF-β1)/Smad and Akt/mTOR/P70S6K Signaling Pathways

BACKGROUND: The related mechanisms involved in allograft interstitial fibrosis and chronic allograft dysfunction (CAD), following renal transplant, remain largely unknown. Here, we explored the role of hepatocyte growth factor (HGF) treatment on the endothelial-to-mesenchymal transition (EndMT) as a...

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Foilsithe in:Ann Transplant
Main Authors: Wang, Zijie, Fei, Shuang, Suo, Chuanjian, Han, Zhijian, Tao, Jun, Xu, Zhen, Zhao, Chunchun, Tan, Ruoyun, Gu, Min
Formáid: Artigo
Teanga:Inglês
Foilsithe: International Scientific Literature, Inc. 2018
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Original Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248046/
https://ncbi.nlm.nih.gov/pubmed/29292365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.906700
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