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Precise A•T to G•C base editing in the zebrafish genome

BACKGROUND: Base editors are a class of genome editing tools with the ability to efficiently induce point mutations in genomic DNA, without inducing double-strand breaks or relying on homology-direct repair as in other such technologies. Recently, adenine base editors (ABEs) have been developed to m...

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Bibliografiske detaljer
Udgivet i:BMC Biol
Main Authors: Qin, Wei, Lu, Xiaochan, Liu, Yunxing, Bai, Haipeng, Li, Song, Lin, Shuo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247682/
https://ncbi.nlm.nih.gov/pubmed/30458760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0609-1
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