Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common prion disease in humans and has been iatrogenically transmitted through corneal graft transplantation. Approximately 40% of sCJD patients develop visual or oculomotor symptoms and may seek ophthalmological consultation. Here we used the hi...

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發表在:mBio
Main Authors: Orrù, Christina D., Soldau, Katrin, Cordano, Christian, Llibre-Guerra, Jorge, Green, Ari J., Sanchez, Henry, Groveman, Bradley R., Edland, Steven D., Safar, Jiri G., Lin, Jonathan H., Caughey, Byron, Geschwind, Michael D., Sigurdson, Christina J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247090/
https://ncbi.nlm.nih.gov/pubmed/30459197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02095-18
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