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MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation

AIMS: It has in recent years been established that epigenetic changes contribute to β-cell dysfunction and type 2 diabetes (T2D). For example, we have showed that the expression of histone deacetylase 7 (HDAC7) is increased in pancreatic islets of individuals with T2D and that increased levels of Hd...

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Foilsithe in:Acta Diabetol
Main Authors: Daneshpajooh, Mahboubeh, Eliasson, Lena, Bacos, Karl, Ling, Charlotte
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Milan 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244806/
https://ncbi.nlm.nih.gov/pubmed/30088095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-018-1201-4
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