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Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

BACKGROUND: Epigenetic factors regulate tissue-specific expression and X-chromosome inactivation. Previous studies have identified epigenetic differences between sexes in some human tissues. However, it is unclear whether epigenetic modifications contribute to sex-specific differences in insulin sec...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Hall, Elin, Volkov, Petr, Dayeh, Tasnim, Esguerra, Jonathan Lou S, Salö, Sofia, Eliasson, Lena, Rönn, Tina, Bacos, Karl, Ling, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256841/
https://ncbi.nlm.nih.gov/pubmed/25517766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0522-z
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