KDM3A histone demethylase functions as an essential factor for activation of JAK2−STAT3 signaling pathway

Janus tyrosine kinase 2 (JAK2)−signal transducer and activator of transcription 3 (STAT3) signaling pathway is essential for modulating cellular development, differentiation, and homeostasis. Thus, dysregulation of JAK2−STAT3 signaling pathway is frequently associated with human malignancies. Here,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kim, Hyunkyung, Kim, Dongha, Choi, Seon Ah, Kim, Chang Rok, Oh, Se Kyu, Pyo, Ki Eun, Kim, Joomyung, Lee, Seung-Hoon, Yoon, Jong-Bok, Zhang, Yi, Baek, Sung Hee
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243239/
https://ncbi.nlm.nih.gov/pubmed/30377265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805662115
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