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Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones

PURPOSE: Previously, compounds containing a piperidone structure have been shown to be highly cytotoxic to cancer cells. Recently, we found that the piperidone compound P2 exhibits a potent anti-neoplastic activity against human breast cancer-derived cells. Here, we aimed to evaluate two piperidone...

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Detalhes bibliográficos
Publicado no:Cell Oncol (Dordr)
Main Authors: Contreras, Lisett, Calderon, Ruben I., Varela-Ramirez, Armando, Zhang, Hong-Yu, Quan, Yuan, Das, Umashankar, Dimmock, Jonathan R., Skouta, Rachid, Aguilera, Renato J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241245/
https://ncbi.nlm.nih.gov/pubmed/30088262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-018-0397-1
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