Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer

Protein homeostasis (proteostasis) is a potential mechanism that contributes to cancer cell survival and drug resistance. Constitutively active androgen receptor (AR) variants confer anti-androgen resistance in advanced prostate cancer. However, the role of proteostasis involved in next generation a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Chengfei, Lou, Wei, Yang, Joy C., Liu, Liangren, Armstrong, Cameron M., Lombard, Alan P., Zhao, Ruining, Noel, Onika D. V., Tepper, Clifford G., Chen, Hong-Wu, Dall’Era, Marc, Evans, Christopher P., Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240084/
https://ncbi.nlm.nih.gov/pubmed/30446660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07178-x
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