Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats

Myostatin gene (MSTN) can inhibit the proliferation of myoblast, which in turn promotes muscle growth and inhibits adipocyte differentiation in livestock. MSTN mutation may lead to muscle hypertrophy or double-muscled (DM) phenotype. MSTN mutation animal, such as sheep, dog, and rabbit have been gen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biosci Rep
Prif Awduron: He, Zhengyi, Zhang, Ting, Jiang, Lei, Zhou, Minya, Wu, Daijin, Mei, Junyan, Cheng, Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239268/
https://ncbi.nlm.nih.gov/pubmed/30201688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180742
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