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Newly Synthesized Polycystin 1 Takes Different Trafficking Pathways to the Apical and Ciliary Membranes
Mutations in the genes encoding polycystin 1 (PC1) and polycysin 2 (PC2) cause Autosomal Dominant Polycystic Kidney Disease (ADPKD). These transmembrane proteins co-localize in the primary cilia of renal epithelial cells, where they may participate in sensory processes. PC1 is also found in the apic...
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| 出版年: | Traffic |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237641/ https://ncbi.nlm.nih.gov/pubmed/30125442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12612 |
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