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A Cut Above (and Below): Protein Cleavage in the Regulation of Polycystin Trafficking and Signaling

The polycystin-1 and 2 proteins, encoded by the genes mutated in Autosomal Dominant Polycystic Kidney Disease, are connected to a large number of biological pathways. While the nature of these connections and their relevance to the primary functions of the polycystin proteins have yet to be fully el...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Padovano, Valeria, Mistry, Kavita, Merrick, David, Gresko, Nikolay, Caplan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269866/
https://ncbi.nlm.nih.gov/pubmed/32283256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109634
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