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Polycystin-1 regulates bone development through an interaction with the transcriptional coactivator TAZ
Polycystin-1 (PC1), encoded by the PKD1 gene that is mutated in the autosomal dominant polycystic kidney disease, regulates a number of processes including bone development. Activity of the transcription factor RunX2, which controls osteoblast differentiation, is reduced in Pkd1 mutant mice but the...
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| Publicado no: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6298236/ https://ncbi.nlm.nih.gov/pubmed/30215740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy322 |
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