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Polycystin-1 C-terminal Cleavage Is Modulated by Polycystin-2 Expression
Autosomal dominant polycystic kidney disease is caused by mutations in the genes encoding polycystin-1 (PC-1) and polycystin-2 (PC-2). PC-1 cleavage releases its cytoplasmic C-terminal tail (CTT), which enters the nucleus. To determine whether PC-1 CTT cleavage is influenced by PC-2, a quantitative...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742866/ https://ncbi.nlm.nih.gov/pubmed/19491093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017756 |
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