Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3(+)RORγt(+) Regulatory T Cells

Foxp3(+) regulatory T cells (Treg) are essential modulators of immune responses, but the molecular mechanisms underlying their function are not fully understood. Here we show that the transcription factor Blimp-1 is a crucial regulator of the Foxp3(+)RORγt(+) Treg subset. The intrinsic expression of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ogawa, Chihiro, Bankoti, Rashmi, Nguyen, Truc, Hassanzadeh-Kiabi, Nargess, Nadeau, Samantha, Porritt, Rebecca A., Couse, Michael, Fan, Xuemo, Dhall, Deepti, Eberl, Gerald, Ohnmacht, Caspar, Martins, Gislâine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237548/
https://ncbi.nlm.nih.gov/pubmed/30282028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados