Differential regulation of Effector and Regulatory T cell function by Blimp1

The transcriptional regulator Blimp1 plays crucial roles in controlling terminal differentiation in several lineages. In T cells, Blimp1 is expressed in both effector (Teff) and regulatory (Treg) cells, and mice with T cell-specific deletion of Blimp1 (Blimp1CKO mice) spontaneously develop severe in...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Bankoti, Rashmi, Ogawa, Chihiro, Nguyen, Truc, Emadi, Lena, Couse, Michael, Salehi, Soofia, Fan, Xuemo, Dhall, Deepti, Wang, Yizhou, Brown, Jordan, Funari, Vincent, Tang, Jie, Martins, Gislâine A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608714/
https://ncbi.nlm.nih.gov/pubmed/28935958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12171-3
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