Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes

Irreversible cartilage collagen breakdown by the collagenolytic matrix metalloproteinases (MMPs)-1 and MMP-13 represents a key event in pathologies associated with tissue destruction such as arthritis. Inflammation is closely associated with such pathology and occurs in both rheumatoid and osteoarth...

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Pubblicato in:PLoS One
Autori principali: Macdonald, Christopher D., Falconer, Adrian M. D., Chan, Chun Ming, Wilkinson, David J., Skelton, Andrew, Reynard, Louise, Litherland, Gary J., Europe-Finner, G. Nicholas, Rowan, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237337/
https://ncbi.nlm.nih.gov/pubmed/30440036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207240
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