The SNARE protein, syntaxin1a, plays an essential role in biphasic exocytosis of the incretin hormone, glucagon-like peptide-1

Exocytosis of the hormone, glucagon-like peptide-1 (GLP-1), by the intestinal L-cell is essential for the incretin effect after nutrient ingestion, and is critical for the actions of dipeptidylpeptidase IV inhibitors that enhance GLP-1 levels in patients with type 2 diabetes. 2-Photon microscopy rev...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Wheeler, Sarah E., Stacey, Holly M., Nahaei, Yasaman, Hale, Stephen J., Hardy, Alexandre B., Reimann, Frank, Gribble, Fiona M., Larraufie, Pierre, Gaisano, Herbert Y., Brubaker, Patricia L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237272/
https://ncbi.nlm.nih.gov/pubmed/28596237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1403
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