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Syntaxin-3 and syntaxin-1A inhibit l-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines
AIMS/HYPOTHESIS: Syntaxin-1A Syn-1A) is known to play a negative regulatory role in insulin secretion but the precise mechanisms for its action are not clear. Syn-2, –3 and –4 are also present in islet beta cells but their functions are not known. Here, we investigated the role of these syntaxins in...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970522/ https://ncbi.nlm.nih.gov/pubmed/11935155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-001-0718-0 |
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