Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells

Syntaxin (Syn)-1A mediates exocytosis of predocked insulin-containing secretory granules (SGs) during first-phase glucose-stimulated insulin secretion (GSIS) in part via its interaction with plasma membrane (PM)-bound L-type voltage-gated calcium channels (Ca(v)). In contrast, Syn-3 mediates exocyto...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xie, Li, Dolai, Subhankar, Kang, Youhou, Liang, Tao, Xie, Huanli, Qin, Tairan, Yang, Lu, Chen, Liangyi, Gaisano, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743851/
https://ncbi.nlm.nih.gov/pubmed/26848587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147862
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