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Cytolytic Activity Score to assess Anticancer Immunity in Colorectal Cancer
BACKGROUND: Elevated tumor infiltrating lymphocytes (TIL) within the tumor microenvironment is a known positive prognostic factor in colorectal cancer (CRC). We hypothesized that since cytotoxic T cells release cytolytic proteins such as Perforin (PRF1) and pro-apoptotic Granzymes (GZMA) to attack c...
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| Pubblicato in: | Ann Surg Oncol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237091/ https://ncbi.nlm.nih.gov/pubmed/29770915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-018-6506-6 |
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