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Cytolytic Activity Score to assess Anticancer Immunity in Colorectal Cancer

BACKGROUND: Elevated tumor infiltrating lymphocytes (TIL) within the tumor microenvironment is a known positive prognostic factor in colorectal cancer (CRC). We hypothesized that since cytotoxic T cells release cytolytic proteins such as Perforin (PRF1) and pro-apoptotic Granzymes (GZMA) to attack c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Surg Oncol
Päätekijät: Narayanan, Sumana, Kawaguchi, Tsutomu, Yan, Li, Peng, Xuan, Qi, Qianya, Takabe, Kazuaki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237091/
https://ncbi.nlm.nih.gov/pubmed/29770915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-018-6506-6
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