Estrogen Receptor Positive Breast Cancer with High Expression of Androgen Receptor has Less Cytolytic Activity and Worse Response to Neoadjuvant Chemotherapy but Better Survival

Estrogen receptor (ER) positive breast cancer (BC), the most abundant BC subtype, is notorious for poor response to neoadjuvant chemotherapy (NAC). The androgen receptor (AR) was reported to support estradiol-mediated ER activity in an in vitro system. Recently, ER-positive BC with fewer tumor infil...

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Pubblicato in:Int J Mol Sci
Autori principali: Okano, Maiko, Oshi, Masanori, Butash, Ali Linsk, Asaoka, Mariko, Katsuta, Eriko, Peng, Xuan, Qi, Qianya, Yan, Li, Takabe, Kazuaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600230/
https://ncbi.nlm.nih.gov/pubmed/31151151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112655
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