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Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer

Due to the loss of DNA repair mechanisms in colorectal cancer (CRC) with microsatellite instability (MSI), somatic mutations accumulate within DNA; making them more prone to attack by tumor infiltrating lymphocytes (TIL) and macrophages. We hypothesize that MSI-High (MSI-H) patients have favorable s...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Narayanan, Sumana, Kawaguchi, Tsutomu, Peng, Xuan, Qi, Qianya, Liu, Song, Yan, Li, Takabe, Kazuaki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748965/
https://ncbi.nlm.nih.gov/pubmed/31530839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49878-4
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