Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer

Due to the loss of DNA repair mechanisms in colorectal cancer (CRC) with microsatellite instability (MSI), somatic mutations accumulate within DNA; making them more prone to attack by tumor infiltrating lymphocytes (TIL) and macrophages. We hypothesize that MSI-High (MSI-H) patients have favorable s...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Narayanan, Sumana, Kawaguchi, Tsutomu, Peng, Xuan, Qi, Qianya, Liu, Song, Yan, Li, Takabe, Kazuaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748965/
https://ncbi.nlm.nih.gov/pubmed/31530839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49878-4
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