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The influence of retinoic acid-induced differentiation on the radiation response of male germline stem cells

Lifelong mammalian male fertility is maintained through an intricate balance between spermatogonial proliferation and differentiation. DNA damage in spermatogonia, for instance caused by chemo- or radiotherapy, can induce cell cycle arrest or germ cell apoptosis, possibly resulting in male infertili...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Zheng, Yi, Lei, Qijing, Jongejan, Aldo, Mulder, Callista L., van Daalen, Saskia K.M., Mastenbroek, Sebastiaan, Hwang, Grace, Jordan, Philip W., Repping, Sjoerd, Hamer, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237089/
https://ncbi.nlm.nih.gov/pubmed/30179733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.027
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