PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival

The germinal center (GC) reaction plays an important role in generating humoral immunity and is believed to give rise to most B-cell lymphomas. GC entry and exit are tightly regulated processes, controlled by the actions of transcription factors such as BCL6. Herein, we demonstrate that protein argi...

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Detaylı Bibliyografya
Yayımlandı:Blood
Asıl Yazarlar: Lu, Xiaoqing, Fernando, Tharu M., Lossos, Chen, Yusufova, Nevin, Liu, Fan, Fontán, Lorena, Durant, Matthew, Geng, Huimin, Melnick, Jacob, Luo, Yuan, Vega, Francisco, Moy, Vincent, Inghirami, Giorgio, Nimer, Stephen, Melnick, Ari M., Lossos, Izidore S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2018
Konular:
Lymphoid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236466/
https://ncbi.nlm.nih.gov/pubmed/30082494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-831438
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