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Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics

The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a serious safety concern for their clinical application. With a set of hESCs with various passage numbers, we observed that a subpopulation of hESCs at late passage numbers was highly resistant to various cell...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Cho, Seung-Ju, Kim, Keun-Tae, Jeong, Ho-Chang, Park, Ju-Chan, Kwon, Ok-Seon, Song, Yun-Ho, Shin, Joong-Gon, Kang, Seungmin, Kim, Wankyu, Shin, Hyoung Doo, Lee, Mi-Ok, Moon, Sung-Hwan, Cha, Hyuk-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235677/
https://ncbi.nlm.nih.gov/pubmed/30293852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.09.002
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