Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

Even when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed therapy-resistance with a large-scale cancer cell transcriptome and drug-response datasets and predicted the candidate drugs...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Hong, Soon-Ki, Lee, Haeseung, Kwon, Ok-Seon, Song, Na-Young, Lee, Hyo-Ju, Kang, Seungmin, Kim, Jeong-Hwan, Kim, Mirang, Kim, Wankyu, Cha, Hyuk-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299529/
https://ncbi.nlm.nih.gov/pubmed/30563517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0924-8
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