Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

Even when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed therapy-resistance with a large-scale cancer cell transcriptome and drug-response datasets and predicted the candidate drugs...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Hong, Soon-Ki, Lee, Haeseung, Kwon, Ok-Seon, Song, Na-Young, Lee, Hyo-Ju, Kang, Seungmin, Kim, Jeong-Hwan, Kim, Mirang, Kim, Wankyu, Cha, Hyuk-Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Letter to the Editor
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299529/
https://ncbi.nlm.nih.gov/pubmed/30563517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0924-8
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi