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Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion
Several neurological disorders may benefit from gene therapy. However, even when using the lead vector candidate for intrathecal administration, adeno-associated virus serotype 9 (AAV9), the strength and distribution of gene transfer to the brain are inconsistent. On the basis of preliminary observa...
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| Publicat a: | Sci Adv |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Association for the Advancement of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6235539/ https://ncbi.nlm.nih.gov/pubmed/30443600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau9859 |
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