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Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques
Transgenic macaques would allow to study brain function and diseases. We report that an engineered adeno-associated virus serotype 9 variant (scAAV9) injected intravenously in newborn rhesus macaques results in efficient, exclusively-neuronal and widespread transduction of the brain. The present dat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275921/ https://ncbi.nlm.nih.gov/pubmed/22355765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00253 |
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