The Retinitis Pigmentosa-Linked Mutations in Transmembrane Helix 5 of Rhodopsin Disrupt Cellular Trafficking Regardless of Oligomerization State

G protein-coupled receptors can exist as dimers and higher-order oligomers in biological membranes. The specific oligomeric assembly of these receptors is believed to play a major role in their function, and the disruption of native oligomers has been implicated in specific human pathologies. Comput...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Mallory, D. Paul, Gutierrez, Elizabeth, Pinkevitch, Margaret, Klinginsmith, Christie, Comar, William D., Roushar, Francis J., Schlebach, Jonathan P., Smith, Adam W., Jastrzebska, Beata
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234845/
https://ncbi.nlm.nih.gov/pubmed/30085663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00403
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi