Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant

BACKGROUND: Controversy is ongoing about whether a minority mutant present at frequencies below 15% may be clinically relevant and should be considered to guide treatment. METHODS: Resistance-associated substitution (RAS) studies were performed in patients before and at failure of antiviral treatmen...

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Publicado en:Infect Drug Resist
Autores principales: Perales, Celia, Chen, Qian, Soria, Maria Eugenia, Gregori, Josep, Garcia-Cehic, Damir, Nieto-Aponte, Leonardo, Castells, Lluis, Imaz, Arkaitz, Llorens-Revull, Meritxell, Domingo, Esteban, Buti, Maria, Esteban, Juan Ignacio, Rodriguez-Frias, Francisco, Quer, Josep
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2018
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233951/
https://ncbi.nlm.nih.gov/pubmed/30519058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S172226
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